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Decoding Metabolism, Advancing Medicine

We investigate how metabolism shapes cellular function, physiology, and disease. Using AI-powered spatial biology, we resolve metabolic networks across tissues and cell types to uncover mechanisms of ageing, cognition, and cancer biology.

Our Research

At the Sun Lab, we explore how metabolism shapes health and disease using cutting-edge spatial molecular techniques. We focus on uncovering metabolic contributions to pediatric sarcoma, dementia, fibrosis, and aging while developing advanced imaging tools for precision biomolecule visualization.

Through diverse collaborations, we tackle complex biomedical challenges and train the next generation of spatial metabolomics leaders. Our ultimate goal is translating discoveries into improved diagnostics and treatments, pioneering insights at the metabolism-disease intersection to drive breakthroughs that advance medicine and improve lives.

Selected Publications from the Sun Lab 

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March 11, 2025

Glycogen drives tumour initiation and progression in lung adenocarcinoma

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May 12, 2025

Spatial mapping of the brain metabolome lipidome and glycome

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March 18, 2025

AI-driven framework to map the brain metabolome in three dimensions

Our Team

Meet the Team Behind the Research

Get to know the students and scientists who power our lab. From undergraduate trainees to senior researchers, our team brings diverse expertise and a shared passion for discovery.

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About Dr. Sun

Dr. Ramon Sun is a biochemist and molecular biologist specializing in metabolism and spatial biology. He earned his Ph.D. from the Australian National University and completed postdoctoral training at Stanford University. He is currently the Anne and Oscar Lackner Endowed Chair and Associate Professor of Biochemistry and Molecular Biology at the University of Florida College of Medicine. He also founded and directs the UF Center for Advanced Spatial Biomolecule Research (CASBR), a nationally leading facility dedicated to high-resolution spatial metabolomics and imaging mass spectrometry. Dr. Sun’s research focuses on how metabolic pathways influence physiology, signaling, and disease progression, particularly in the brain and cancer. His lab integrates spatial metabolomics with AI-driven analysis to uncover cell- and tissue-specific mechanisms underlying neurological, neoplastic, and age-related disorders.

Ramon Sun

Principal Investigator

We're Recruiting!

Looking for an exciting and fulfilling research opportunity using cutting-edge technologies?

Join Dr. Sun’s lab at the University of Florida, where we explore innovative solutions at the intersection of imaging and metabolomics. We welcome undergraduate and graduate students from all backgrounds—prior research experience is not required. What matters most is your curiosity, willingness to learn, and drive to grow as a scientist.

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