Publications

Molecular Cancer Therapeutics

2015

The PI3K/Akt Pathway Regulates Oxygen Metabolism via Pyruvate Dehydrogenase (PDH)-E1α Phosphorylation

Cerniglia, G.J., Dey, S., Gallagher-Colombo, S.M., Daurio, N.A., Tuttle, S., Busch, T.M., Lin, A., Sun, R.C., Esipova, T.V., Vinogradov, S.A., Denko, N., Koumenis, C., Maity, A.

Link to Article

Oral Surgery Oral Medicine Oral Pathology and Oral Radiology

2015

Construction of a Fluorescent Reporter Gene for the Analysis of OGDH2 Protein Stability in Hypoxia

Link

O'Neill, W., Sun, R.C., Papandreou, I., Kalmar, J., Denko, N.

Link to Article

Cell Metabolism

2014

Hypoxic Regulation of Glutamine Metabolism through HIF1 and SIAH2 Supports Lipid Synthesis that Is Necessary for Tumor Growth

Link

Sun, R.C., Denko, N.C.

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Molecular Cancer

2011

Targeting metabolism with arsenic trioxide and dichloroacetate in breast cancer cells

Link

Sun, R.C., Board, P.G., Blackburn, A.C.

Link to Article

Breast Cancer Research and Treatment

2010

Reversal of the glycolytic phenotype by dichloroacetate inhibits metastatic breast cancer cell growth in vitro and in vivo

Link

Sun, R.C., Fadia, M., Dahlstrom, J.E., Parish, C.R., Board, P.G., Blackburn, A.C.

Link to Article

Pathology

2010

Reversal of the glycolytic phenotype with dichloroacetate in a mouse mammary adenocarcinoma model

Link

Blackburn, A.C., Rooke, M., Sun, R.C., Fadia, M., Dahlstrom, J.E., Board, P.G.

Link to Article

American Association for Cancer Research

2009

New drug combinations to target the Warburg effect in cancer therapy

Link

Sun, R.C., Board, P.G., Blackburn, A.C.